Andropause, also called late onset hypogonadism or low testosterone, is a term for the condition associated with the natural decrease in the hormone testosterone in men. This decrease in testosterone can lead to physical, emotional, physiological, and behavioral changes in men as they age. Typically, men go through these changes slowly over time, but they can appear suddenly in some circumstances. In some men, their production of testosterone will begin decreasing as early as their 30’s and will continue to decrease by 1% – 2% each year.

Symptoms of Andropause

  • Decreased energy
  • Decreased sex drive
  • Decreased muscle strength
  • Increased body fat
  • Erectile dysfunction
  • Mood swings
  • Osteoporosis or decreased bone density

While all of these are symptoms of Andropause, they could also be symptoms of other diseases or conditions that a person is experiencing. Proper testing is important to accurately diagnose low testosterone levels.

Treatment Options

  • Transdermal medications are applied topically to the skin and absorbed through it. Transdermal creams or gels can be tailored to each individual to provide the dose each person needs.
  • Testosterone injections are typically injected directly into the muscle. Injections are usually performed every 1 to 2 weeks. The injections produce testosterone levels that are above the normal level initially after injection, and then levels fall into the normal range over the next 7-14 days.


It is important for patients to be properly monitored while on testosterone replacement therapy. Monitoring includes evaluating serum testosterone levels, hematocrit, and Prostate Specific Antigen (PSA) for some men.

Erectile Dysfunction

It is estimated that at least 20 million men in the U.S. suffer from erectile dysfunction (ED). Most men affected by ED are over the age of 40, but it can affect men of any age.


  • Low testosterone
  • Diabetes
  • Prostate Issues
  • High Blood Pressure or other cardiovascular disease
  • Other medications
  • Smoking or Alcohol use

Treating ED

  • PDE5i’s
    Oral medications like tadalafil and sildenafil are often the first-line medications used to treat ED. These medications may work well for some men, but they also come with a variety of side effects like headache, flushing, back pain, nasal congestion, and upset stomach. They may also be contraindicated with other medications like nitrates or certain beta blockers.
  • Trimix (Papaverine, Phentolamine, and Alprostadil)
    Some men may not respond to oral ED medications or may not be able to tolerate the side effects from taking them. For patients who either cannot or do not want to take oral medications for ED, a compounded injectable medication can be the best option. Trimix is a combination of 3 active ingredients (Papaverine, Phentolamine, and Alprostadil) that work together to dilate the blood vessels and relax the smooth muscle of the penis to cause an erection. For most men, the idea of injecting medication into the penis is an uncomfortable thought; however, most men find that the process is very easy and almost painless.

Trimix Benefits

    • Quicker onset of action
    • Long-Lasting
    • Easy to Use

Let one of our knowledgeable pharmacists help guide you in the process of finding the right ED treatment for you.